Complete the Animus testing sequence without failing (The Lost Archive).
Break the loop, escape the cycle (The Lost Archive).
Experience the loop (The Lost Archive).
Find all of the decipher fragments (The Lost Archive).
Make it across the river Styx without failing (The Lost Archive).
Finish memory five (The Lost Archive).
Enter the Animus simulation (The Lost Archive).
Reach the Animus memo (The Lost Archive).
Take the induction leap of faith (The Lost Archive).
Land on a block after falling more than 25 meters (The Lost Archive).
Collect all available books.
Have 10 guards poisoned at the same time.
Perform a perfect Den Defense without using the cannon.
Complete all Faction Creed Challenges from a single faction.
Loot 50 dead guards with thief looting.
Parachute onto a zipline.
Kill 5 guards in 5 seconds using only your hidden blades.
Kill 5 guards while under the cover of a smoke screen bomb.
Have a guard incapacitate 3 civilians while he's poisoned.
Craft 30 bombs.
Kill three guards simultaneously with only throwing knives.
Complete Desmond Sequence 5.
Complete Desmond Sequence 4.
Complete Desmond Sequence 3.
Collect all Animus data fragments.
Get your money back from a Templar tax collector.
Parachute directly from the top of the Galata Tower to the Golden Horn.
Have seven trainees reach the rank of Master Assassin.
Kill 5 guards with a scaffold after they have been stunned by caltrops.
Complete all Bomb Missions.
Complete the Hagia Sofia challenge level.
Climb Hagia Sofia, from the ground to the pinnacle, in under 25 seconds.
Collect all of Ishak Pasha's memoir pages.
Find and beat up Duccio.
Achieve 100% Synchronization in all Sequences.
Complete DNA Sequence 9.
Complete DNA Sequence 8.
Complete DNA Sequence 7.
Complete Desmond Sequence 2.
Complete DNA Sequence 6.
Control all cities (except Rhodes) simultaneously in the Mediterranean Defense game.
Complete Desmond Sequence 1.
Complete DNA Sequence 5.
Complete DNA Sequence 4.
Have one trainee reach the rank of Master Assassin.
Complete DNA Sequence 3.
Assassinate 50 guards with the hidden blade.
Beat up the 5 thirsty harlequins.
Throw a Long Weapon, Heavy Weapon, and Smoke bomb more than 10 m at a guard.
Double Assassinate from a parachute.
Kill a guard with a broom.
Solve all of Subject 16's Puzzles.
Remove All Borgia Flags in Rome.
Receive 100% synch in ACB and full synch in all missions of The Da Vinci Disappearance.
Steal 5 horses from their riders, while remaining on horseback.
Win the highest bet at the Fights.
Win 10,000 florins playing Hazard.
Kill 10 guards with a single arrow storm.
Complete The Da Vinci Disappearance.
Collect All Feathers.
Jump with the parachute off the top of Castel Sant'Angelo.
Destroy the Tank.
Complete 10 Guild Challenges.
Kill a guard with the bag that drops from a lift.
Discover the Shrine in the Cloaca Maxima.
Destroy the Bomber.
Destroy the Naval Cannon.
Train a recruit up to the Rank of Assassin.
Discover the Shrine in Il Colosseo.
Complete DNA Sequence 2.
Complete DNA Sequence 1.
Earn 3 gold medals in the Animus Virtual Training Program.
Discover the Shrine in Palazzo Laterano.
Burn All Borgia Towers.
Secure the Apple of Eden.
Discover the Shrine in the Basilica di San Pietro.
Throw money in a well.
Pay 500 florins to an orator, then pickpocket him afterward.
Destroy the Machine Gun.
Renovate 5 buildings in the Antico district.
Recruit 3 Assassins.
Discover the Shrine in the Catacombe di Roma.
Achieve 100% Synchronization in any Sequence other than Sequence 1.
Replay a Memory.
Find 1 Artifact in 2012.
Access your email in 2012.
Discover the Shrine in the Terme di Traiano.
Perform an Execution Streak of 10 kills.
Find a secure place to hide and re-enter the Animus.
Attempt to access DNA Sequence 9 for the first time.
Reach 80% of your stronghold's total value.
Wear the Auditore cape in each city.
Perform an Air Assassination on a Poisoned NPC.
Kill 10 enemies while remaining in conflict without being hit.
Collect all the Feathers.
Unlock all 20 pieces of Subject 16's video.
Sweep 5 guards at once by using a Long Weapon.
Tint your clothes with those colors: Wetland Ebony and Wetland Ivory.
Get all Hidden Blades, Item Pouches and Armor upgrades for Ezio.
Escape the hideout.
Complete DNA Sequence 14.
Find the 8 statuettes in Monteriggioni.
Perform a Leap of Faith from the Top of Florence's Giotto's Campanile.
Buy a Painting from Florence and Venice.
Hide 5 dead bodies in a Bale of Hay.
Defend a woman's honor.
Complete DNA Sequence 11.
Complete DNA Sequence 10.
Win a race against thieves.
Toss more than 300 florins on the ground.
Pickpocket 1000 Florins.
Stun 4 guards at once by throwing sand in their face.
Complete your first assassination mission for Lorenzo Il Magnifico.
Spend 5000 florins on Courtesans.
Discover the Assassin's Tomb inside Santa Maria della Visitazione.
Kick a guard while using the Flying Machine.
Discover the Assassin's Tomb inside the Basilica di San Marco.
Intercept a Borgia Courrier.
Complete training and reenter the Animus.
Discover the Assassin's Tomb inside the Rocca di Ravaldino fortress.
Discover the Assassin's Tomb inside the Torre Grossa.
Discover the Assassin's Tomb inside Santa Maria del Fiore (The Duomo).
Discover the Assassin's Tomb inside the catacombs under Santa Maria Novella.
Upgrade a building in the Stronghold.
Synchronize 10 View Points.
Unlock a piece of Subject 16's video.
Use your Eagle Vision to scan a Glyph in the environment.
Sprint for 100 meters.
Enter the Animus 2.0.
Break out of Abstergo.
Be reborn as Ezio Auditore da Firenze.