Complete Not a Hero on Professional difficulty.
Complete Not a Hero on Easy or Normal difficulty.
Unlock all trophies.
Get ending 2.
Read all of the files in a single playthrough.
Fight off Marguerite while she wanders the old house to make her run away.
Take down two or more enemies with one shot.
Complete the "Happy Birthday" videotape within 5 minutes.
Get ending 1.
Complete the game using only 3 First Aid Meds or less.
Complete the game without opening the Item Box more than 3 times.
Increase your item slots.
Complete the "Mia" videotape without being spotted by Marguerite.
Complete Survival mode in 21.
Complete 21.
Get the true ending in Daughters.
Get the bad ending in Daughters.
Use psychostimulants.
Create all items that contain Chem Fluid and Strong Chem Fluid.
Obtain all of the Antique Coins in Madhouse difficulty.
Block an enemy attack by guarding.
Kill an enemy by attaching a Remote Bomb to them and detonating it.
Avoid Jack's scissor attack by crouching.
Use a lock pick to open something.
Put an unrelated object on a shadow plinth.
Obtain something by closely examining an item.
Close an open door by yourself.
Finish off an enemy with the knife.
Clear insects off a door using a knife.
Obtain all of the Antique Coins in Easy or Normal difficulty.
Watch all the videotapes in a single playthrough.
Escape from the ship.
Escape from the Baker family home.
Uncover the secret in the old house.
Escape to the yard.
Escape from the guest house.
Travel to Louisiana.
Shoot and knock back Marguerite while she's leaping at you.
Complete the game within 4 hours.
Complete the game on Madhouse.
Complete the game on Normal.
Complete the game on Easy.
Destroy all Mr. Everywhere statuettes.
Destroy a Mr. Everywhere statuette.
Complete Nightmare.
Complete Night Terror.
Complete Bedroom.
Find all the dead rats in Bedroom in a single play.
Complete Ethan Must Die.
Complete Survival+ mode in 21.
Clear a stage with a 10 minute time bonus or higher in Jack's 55th Birthday.
Feed Jack every type of food and drink in Jack's 55th Birthday.
Get an S Rank or higher on all stages in Jack's 55th Birthday.
Complete End of Zoe on Easy or Normal.
Complete End of Zoe on Joe Must Die.
Complete End of Zoe on Normal or Joe Must Die using no weapons.
Complete an Extreme Challenge in End of Zoe.
Perform a 4-hit combo with your bare fists in End of Zoe.
Stealth kill 5 enemies in End of Zoe.
