Collect 25 specks of dust.
Complete Franklin's Flashback.
Visit every floor in the hotel.
Begin Part Three.
Read all the Thimbleweed Nickel newspapers.
Escape from the sewers.
Complete Delores's Flashback.
Read 100 books in the library.
Listen to 100 Voicemail messages.
Complete Ransome's Flashback.
Push the circus mime over.
Begin Part Two.
Begin Part One.
Collect all trophies.
Catch the killer.
Begin Part Four.
Get an alive character into the Hotel penthouse.
Begin Part Five.
Begin Part Six.
Begin Part Seven.
Begin Part Eight.
Begin Part Nine.
Complete the game in casual mode.
Complete the game in hard mode.
Stay for all the credits.
Use Ransome's Itch Cream.
Blow up the Mansion.
Collect 50 specks of dust.
Make everyone cry about their life.
Navigate to the buried treasure.
Grow Leonard's plant to superhuman size.
Collect 75 specks of dust.
Get Ransome's bad ending.
Don't pick up any specks of dust.