Apply 99 or more Poison on a single enemy.
Unlock Ascension mode.
Beat the game with the Silent.
Defeated the Awakened One.
Defeat a boss without taking any damage.
Defeated the Bronze Automaton.
Exhaust 20 cards in a single combat.
Defeat 3 enemies with Poison in a single combat.
Have 9 Energy during a single turn of combat.
Win a combat without playing an Attack.
Defeated the Collector.
Defeated the Guardian.
Defeated the Champ.
Defeated the Slime Boss.
Win a battle with 1 HP remaining.
Defeated Hexaghost.
Obtain all other Trophies.
Play 10 Shivs in a single turn.
Play 25 cards in a single turn.
Defeat a boss on turn 1.
Have 3 or fewer cards in hand, draw, and discard pile combined.
Defeated Donu & Deca.
Defeated the Time Eater.
Beat the game with the Ironclad.
Beat the game with a single relic.
Beat the game in under 20 minutes.
Complete Ascension Level 10.
Beat the game with a 5 card deck or smaller.
Finish Donu with a Feed.
Beat the game with the Defect.
Beat the game with a deck containing no uncommons or rares.
Have 25 or more Focus during combat.
Channel 9 Plasma in a single turn.
Defeat the Transient before it fades away.
Complete Ascension Level 20.
Complete the Ending with the Ironclad.
Complete the Ending with the Silent.
Complete the Ending with the Defect.
Complete the Ending with the Ironclad, Silent, and Defect.
Win a Daily Climb.
Beat the game with the Watcher
Complete the Ending with the Watcher
Have 10 or more buffs during combat.
Have 50 or more Strength during combat.
Have 99 or more Block during combat.
Have 999 Block during combat.