Earned all of the game's trophies
Find all the Comic Stacks
Play as Squirrel Girl in a back Issue
Complete a panel using Scarlet Witch, Squirrel Girl, and Invisible Woman
Bring Squirrel Girl into the final fight against Doom
Complete Issue 6
Defeat Doctor Doom in the end boss battle
Complete Issue 5
Sell 1,000,000 issues
Pick up 1,000 Hero Points
Land the final blow on a Brute with Wolverine
Open a Factor Lock for each Factor
Complete Issue 4
Hit six targets with one hex using Scarlet Witch
Pick up 75 Hero Points in a single panel
Use a glyph bomb to defeat 5 or more enemies at the same time
Defeat 3 or more enemies with one glyph ball roll
Use Hulk to destroy 25 breakables
Complete a panel with all heroes in alternative costumes
Complete a panel using Wolverine, Reptil, and Hulk
Start a panel with a hero wearing an alternate costume
Complete Issue 3
Use Hero Up! to defeat 6 or more enemies
Complete Issue 2
Survive the laser hallway without getting hit by laser
Find 5 Comic Stacks
Use Hero Up! five times in one issue
Use a decoy to distract 3 or more enemies at the same time
Use an Earthquake to defeat 5 or more enemies
Defeated 5 enemies simultaneously
Use Hero Up!
Use two decoys simultaneously
Complete Issue 1
Pick up a health pack when a hero is about to be defeated
Revive a hero to full health
Exit a panel with a full ink meter and all heroes at full health
Sell 7,000 issues in a single panel
Sell 10,000 issues
Use a single ink attack to defeat 2 or more enemies
Drain two full bars of ink in a single attack
Defeat an enemy using only Hold abilities
Sell 1,000 issues
