Acquire all trophies
Use biotic Lift 75 times
Use biotic Singularity 75 times
Use biotic Stasis 75 times
Use biotic Barrier 75 times
Use biotic Warp 75 times
Use biotic Throw 75 times
Use Neural Shock 75 times
Use AI Hacking 75 times
Use Damping Field 75 times
Use Sabotage 75 times
Use Shield Overload 75 times
Complete the majority of the game with the krogan squad member
Reach 60th level with one character
Complete the majority of the game with the turian squad member
Use medi-gel 150 times
Complete 1 Mass Effect playthrough on the Insanity difficulty setting. Do not change the setting.
Complete 1 Mass Effect playthrough on the Hardcore difficulty setting. Do not change the setting.
Complete 2 Mass Effect Playthroughs on any setting
Complete the majority of the game with the quarian squad member
Complete the majority of the game with the Alliance sentinel squad member
Accumulate 75% of total Renegade points
Reach 50th level with one character
Register 150 Sniper Rifle Kills
Complete 1 Mass Effect Playthrough on any setting
Complete playthrough with shield damage greater than health damage
Complete any romance subplot
Complete the majority of the game with the asari squad member
Complete Virmire
Register 150 Pistol Kills
Use Charm or Intimidate to resolve an impossible situation
Complete Noveria
Complete the majority of the game with the Alliance soldier squad member
Complete the majority of the game
Complete the Bring Down the Sky mission.
Accumulate 75% of total Paragon points
Register 150 Assault Rifle Kills
Exceed 1,000,000 Credits
Register 150 Shotgun Kills
Register 250 synthetic enemy kills
Complete Feros
Register 150 organic enemy kills
Land on an uncharted world
Find all primary Alien: Council Races, Extinct Races and Non-Council Races codex entries
Locate Dr. T'soni in the Artemis Tau cluster
Become a Spectre
Complete Eden Prime