Earn all Trophies to please the Emperor of Mankind.
Kill 2500 Horde type enemies.
Execute 50 enemies (only with Assassin or Crusader).
Create 100 Warp anomalies (Psyker only).
Achieve "Killstreak" bonus 30 times.
Achieve "Massacre" bonus for the first time.
Get "Angel of Death" bonus 30 times.
Get "Unbreakable" bonus 30 times.
Complete 50 multiplayer missions.
Complete a mission in local coop.
Revive each other 50 times.
Complete 25 side events during the missions.
Kill 250 Champion enemies.
Complete a Priority Assignment on Impossible difficulty or higher.
Complete 25 missions without dying.
Complete 5 Priority Assignments.
Complete an entire Priority Assignment sequence without dying.
Complete 10 Investigations on the highest difficulty.
Complete at least one mission from every type on the StarMap.
Complete 10 Void Crusade missions.
Join a Cabal.
Complete 10 Cabal directives with your Cabal.
Deal with 50 traps.
Kill 100 Elite creatures.
Open 100 supply chests.
Blow up 250 explosive containers.
Use Booster type Inoculator component 250 times.
Equip your first Relic item.
Craft 25 items.
Fuse a socket into a Relic item.
Acquire 5000 Fate points.
Reach Inquisitorial Rank 20 with at least one character.
Learn all the skills from a single Skill tree.
Unlock all Skill trees.
Kill 50 Commander enemies.
Research 10 Tech tree upgrades.
Reach Inquisitorial Rank 50 and complete a mission in a Warzone.
Reach maximum points in a Weekly Glory challenge.
You have saved Caius Thorn and left the "Martyr".
You have found Metrodora Thelema.
You have found Omicron Arkh.
You have unlocked Uther's Tarot.
You have found Lord Inquisitor Klosterheim.
You have senteced Klosterheim to death.
You have released Klosterheim.
Kill 5 Boss creatures.
You have killed Flavius Draken.
You have released Flavius Draken.
You have found the Rosette of Uther Tiberius.
You have entered the Stasis Chamber.
You have left the Alpha Pariah with Lord Klosterheim.
You have left the Alpha Pariah with the Machine Spirit of the "Martyr".
You have made a decision regarding the fate of a Psyker in the service of the Drukhari.
You have sabotaged the Drukhari master plan and destroyed all of the Pain Catalysts.
You have eradicated the Coterie of Dissonance from the Triglav Subsector.
Kill 1000 Dark Eldar enemies.
Kill 50 enemies while they are in cover.
Destroy 100 Pain Catalysts in City of Suffering (DLC required).
Reach 1500 Score in City of Suffering (DLC required).
Unlock the "Agartha" Subsector.
You have judged Caius Thorn for his disobedience.
You have destroyed Abraxas, the infamous Chaos Knight.
You have killed Kairn Golgarth, the Voidripper warlord.
Kill 1000 Khorne enemies.
Kill 2500 Enemies by your Kastelan Robots (Tech-Adept only).
Kill 20 Elite enemies on your level or higher (Tech-Adept only).
Complete a mission dealing damage only by your Construct turrets on your level or higher (Tech-Adept only).
Kill 1000 enemies with grenade.
Complete 5 missions without taking any Melee damage (Tech-Adept only).
Summon 1000 Constructs (Tech-Adept only).
Complete 25 missions without losing a single Construct (Tech-Adept only).
You have discovered the mysterious "Martyr" (Tech-Adept only).
You have survived the first encounter with Fabius Bile.
You have seized the ancient prophecy about the Alpha Pariah.
You have judged the renegade Tech-Priest known as the "Savant".
You have closed the Dark Nexus and witnessed the fate of the Alpha Pariah.
Kill 5000 enemies with ranged skills.
Kill 5000 enemies with melee skills.