Have a Level 10 Hospital
Cure 1 Patient
Collect every Trophy in Two Point Hospital
Earn 15 Gold Stars
Earn 30 Gold Stars
Earn 45 Gold Stars
Reach $50,000,000 Organisation Value
Earn 10,000 Kudosh
Have a Level 20 Hospital
Win every award in a single hospital
Shoot 1 Monobeast
Shoot 10 Monobeasts in a row without missing
Cure 1000 Patients
Injure someone with an exploding machine
Earn 1 Star at each hospital in the Pointy Mountains
Earn 54 Gold Stars
Complete the "Cheesier Gubbins" Research Project in Swelbard
Have a Level 5 De-lux Clinic at the Underlook Hotel
Knock the socks off of Bartholomew F. Yeti
Get a Curing Spree on Topless Mountain
Earn 63 Gold Stars
Earn 1 Star at each hospital on Pebberley Island
Complete Wave 42 on Topless Mountain
Train a World-Class Researcher
Unlock every plot in Overgrowth
Complete a Multiplayer Challenge
Complete Superbug Project "Hair Removal"
Complete 50 Research Nodes
Earn 72 Gold Stars
Expose 50 Alien Infiltrators
Activate every Robo-Janitor prototype in Chasm 24
Cure a patient with Frogborne
Earn 1 Star at each hospital in Close Encounters
Cure a patient in the Herb Garden
Train a World-Class Psychiatrist
Earn 81 Gold Stars
Maximise your Green Energy capacity in Windsock
Receive the highest possible Eco Rating
Earn 1 star at each hospital in Off The Grid
Complete R.E.M.I.X versions of Hogsport, Lower Bullocks & Flottering
Complete R.E.M.I.X versions of Mitton University, Tumble & Flemington
Train a World-Class Surgeon
Complete 50 Research Projects
Run 50 Marketing Campaigns
Conduct 25 Machine Upgrades
Capture 100 Ghosts