Equip 8 items at rank 7 (Relic) at the same moment
Collect 10 000 Pieces of Eight
Choose the destiny of Captain Pennington
Defeat the Puppeteer
Reaffirm your Oath
Defeat Aul' Saul
Choose the destiny of Fairefax Haskell
Defeat the Infamy
Defeat 50 enemies with a Banishment
Upgrade an item at rank 7 (Relic)
Defeat 3 enemies with a single Outburst
Defeat 8 enemies in a single encounter without being hit
Destroy 300 destructibles
Defeat 5 enemies with a weakspot hit (Rifle) in a single encounter
Complete the same Ritual site 10 times (intensity level 10)
Defeat 3 enemies with a post parry attack in a single encounter
Choose the destiny of Thickskin
Defeat the Beast
Defeat at least 4 enemies with Red and at least 4 enemies with Antea in a single encounter
Take your Oath
Upgrade an item
Find Antea
Defeat the mighty master
Collect 5 ores
Eliminate an enemy with the Dimensional Claw
Eliminate 5 enemies by throwing them into spikes
Defeat the banished god
Earn 10,000 Time Crystals
Defeat the otherworldly queen
Eliminate the Jailer
Eliminate 20 enemies with an opportunity attack
Defeat an alternate version
Defeat the king of beasts
Eliminate 30 enemies in the air
Caught Pal for the first time
Defeat a Lost Warrior
Take Songbird to the stars.
Complete “Run This Town”.
Kill or incapacitate 3 enemies in quick succession with a revolver or pistol in close combat.
Complete every Gig in Dogtown.
Kill or incapacitate 50 enemies while time is slowed.
Steal the Arasaka medical truck or deliver 10 vehicles to El Capitan.
Eliminate three bosses from the "Increased criminal activity" category.
Defeat the Chimera.
Save President Myers.
Craft 3 Legendary items.
Complete the main campaign.
Complete the quest Rising Pressure.
Unlock an Apex Skill.
Defeat a thanator (non-feral)